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Please match the medication to its mechanism of action.
- 5-Fluorouracil (e.g., Efudex)
- Imiquimod (e.g., Aldara)
- Picato (ingenol mebutate)
interrupts the growth of rapidly dividing cells (such as cancer) by mimicking thymine
increases immune activity where applied by raising levels of Interleukins, TNF, and Interferon
plant extract which acts as "an inducer of cell death"
Imiquimod is only prescribed for the treatment of skin cancer.
The exact manner (frequency, duration, etc.) in which Imiquimod and 5-Fluorouracil are prescribed varies significantly, depending on the condition being treated and the preferences of the prescribing physician.
Two different patients came in this morning for re-evaluation after undergoing treatment with Efudex 3 months ago. The first patient reported that he experienced significant inflammation during treatment. The other patient reported that she experienced only mild-to-moderate inflammation. What’s the most likely explanation for the difference in their experiences?
The above patient walks in the clinic asking to see a nurse. He’s been using Imiquimod for the past 2 weeks to treat AKs on the face. The areas “sting” a little, but he’s otherwise not in significant discomfort. What would be the most appropriate manner of handling this situation?
It is ___________ to provide clear, specific instructions to those who are prescribed either 5-Fluorouracil or Imiquimod.
Two months ago, your supervising physician prescribed Efudex (5-Fluorouracil) to a female patient to apply to a cluster of warts on the bottom of her foot. She calls the office today asking if it’s OK to continue using because she just found out that she’s pregnant. Which of the following responses is most appropriate?
Which of the following medications has the shortest treatment duration for actinic keratoses?
Please match the appropriate Picato concentration to the treatment sites for which it’s approved.
- Picato 0.015% Gel
- Picato 0.05% Gel